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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
25.76
Human Site:
S73
Identified Species:
51.52
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
S73
Q
K
A
L
K
V
T
S
L
P
A
M
T
D
R
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
S73
Q
K
A
L
K
V
T
S
L
P
A
M
T
D
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
S73
Q
K
A
L
K
V
T
S
L
P
A
M
T
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
S73
Q
K
A
L
K
V
T
S
L
P
A
M
T
D
R
Rat
Rattus norvegicus
NP_001127833
1567
166392
N73
L
E
S
I
A
R
Q
N
G
L
G
S
H
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
Chicken
Gallus gallus
XP_418125
1594
169410
S85
Q
K
A
L
K
V
S
S
L
P
A
M
T
D
R
Frog
Xenopus laevis
Q6INP8
1570
165663
N73
L
E
S
I
A
R
Q
N
G
L
T
S
H
L
S
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
M72
S
K
V
I
R
Q
A
M
E
K
R
G
A
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
K23
H
I
P
S
I
E
E
K
N
K
Q
I
Q
Q
E
Honey Bee
Apis mellifera
XP_395879
1811
193227
S88
Q
H
S
I
K
V
T
S
L
Q
S
M
V
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
S88
K
M
A
I
K
V
T
S
V
P
A
M
N
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
0
93.3
0
6.6
N.A.
0
53.3
N.A.
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
0
100
26.6
20
N.A.
6.6
80
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
17
0
9
0
0
0
50
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% D
% Glu:
0
17
0
0
0
9
9
0
9
0
0
0
0
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
17
0
9
9
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
9
0
42
9
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
9
50
0
0
59
0
0
9
0
17
0
0
0
0
0
% K
% Leu:
17
0
0
42
0
0
0
0
50
17
0
0
0
17
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
0
59
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
9
0
0
0
9
0
9
% N
% Pro:
0
0
9
0
0
0
0
0
0
50
0
0
0
0
0
% P
% Gln:
50
0
0
0
0
9
17
0
0
9
9
0
9
9
0
% Q
% Arg:
0
0
0
0
9
17
0
0
0
0
9
0
0
0
59
% R
% Ser:
9
0
25
9
0
0
9
59
0
0
9
17
0
0
17
% S
% Thr:
0
0
0
0
0
0
50
0
0
0
9
0
42
0
0
% T
% Val:
0
0
9
0
0
59
0
0
9
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _